MolNFT v1 · #56959 · protein

Structure of the periplasmic domain of motb from salmonella (crystal form III)

2ZVZ · Chemotaxis protein motb: “Structure of the periplasmic domain of motb from salmonella (crystal form III)”. X-ray diffraction, 4 pockets (best druggability 0.74). MolNFT v1 #56959 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 2ZVZ
Type: protein
Length: 331 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chemotaxis protein motb
UniProt: P55892
Pockets: 4 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 43% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chemotaxis protein motb	protein	170	41% helix, 21% strand	P55892
B	Chemotaxis protein motb	protein	161	45% helix, 22% strand	P55892

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	597	0.74	0.81	73	empty
2	95	0.38	0.76	21	empty
3	62	0.32	0.76	17	empty
4	55	0.26	0.73	14	empty

Interfaces

1 interface between chains.

A–B · 1123 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

2ZVZ · Structure of the periplasmic domain of MotB from Salmonella (crystal form III) · the same entry in another collection · chain A against A, TM-score 1.00
P55892 · AlphaFold monomer V2.0 prediction for motility protein B (P55892) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55892
Elsewhere: RCSB PDB 2ZVZ · PDBe 2ZVZ · UniProt P55892

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