MolNFT v1 · #56788 · protein

Crystal structure of secye translocon from thermus thermophilus

2ZQP · Preprotein translocase secy subunit: “Crystal structure of secye translocon from thermus thermophilus”. X-ray diffraction, 8 pockets (best druggability 0.80). MolNFT v1 #56788 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2ZQP
Type: protein
Length: 461 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Preprotein translocase secy subunit; Preprotein translocase sece subunit
UniProt: Q8KZP3, Q8KZP4
Pockets: 8 · best druggability 0.80

Structure

x-ray diffraction · 2 distinct chains · 56% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
Y	Preprotein translocase secy subunit	protein	415	57% helix, 2% strand	Q8KZP3
E	Preprotein translocase sece subunit	protein	46	41% helix, 2% strand	Q8KZP4

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	941	0.80	0.81	92	empty
2	410	0.68	0.80	54	empty
3	135	0.66	0.87	18	empty
4	141	0.50	0.78	22	empty
5	112	0.47	0.80	22	empty

Interfaces

1 interface between chains.

Y–E · 1790 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

2ZQP · Crystal Structure of SecYE translocon from Thermus thermophilus · the same entry in another collection · chain Y against Y, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8KZP3
Every structure of UniProt Q8KZP4
Elsewhere: RCSB PDB 2ZQP · PDBe 2ZQP · UniProt Q8KZP3 · UniProt Q8KZP4

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