MolNFT v1 · #56509 · protein
Crystal structure analysis of the sodium-bound annexin A4 at 1.58 a resolution
2ZHI: “Crystal structure analysis of the sodium-bound annexin A4 at 1.58 a resolution”. X-ray diffraction, 2 ligands (NA, SO4), 4 pockets (best druggability 0.55). MolNFT v1 #56509 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2ZHI
- Type
- protein
- Length
- 315 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Annexin A4
- UniProt
- Q5U362
- Ligands
- NA, SO4
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Annexin A4 | protein | 315 | 74% helix, 0% strand | Q5U362 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 160 | 0.55 | 0.81 | 26 | empty |
| 2 | 72 | 0.46 | 0.83 | 20 | empty |
| 3 | 82 | 0.41 | 0.79 | 17 | empty |
| 4 | 68 | 0.34 | 0.77 | 20 | empty |
Compared structures
- 2ZHI · Crystal Structure Analysis of the Sodium-Bound Annexin A4 at 1.58 A resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5U362
- Elsewhere: RCSB PDB 2ZHI · PDBe 2ZHI · UniProt Q5U362
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