MolNFT v1 · #56374 · protein

D202K mutant of P. denitrificans ATP12P

2ZD2 · ATP12 ATPase: “D202K mutant of P. denitrificans ATP12P”. X-ray diffraction, 8 pockets (best druggability 0.52). MolNFT v1 #56374 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2ZD2
Type: protein
Length: 468 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ATP12 ATPase
UniProt: A1B060
Pockets: 8 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 60% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	ATP12 ATPase	protein	234	60% helix, 9% strand	A1B060

Pockets

8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	310	0.52	0.74	38	empty
2	167	0.43	0.74	24	empty
3	74	0.35	0.76	16	empty
4	63	0.32	0.76	17	empty
5	81	0.31	0.73	20	empty

Interfaces

1 interface between chains.

A–B · 236 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

2ZD2 · D202K mutant of P. denitrificans Atp12p · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A1B060
Elsewhere: RCSB PDB 2ZD2 · PDBe 2ZD2 · UniProt A1B060

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