MolNFT v1 · #56361 · protein
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from staphylococcus aureus
2ZCO: “Crystal structure of the C(30) carotenoid dehydrosqualene synthase from staphylococcus aureus”. X-ray diffraction, 3 pockets (best druggability 0.75). MolNFT v1 #56361 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2ZCO
- Type
- protein
- Length
- 284 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dehydrosqualene synthase
- EC
- 2.5.1.-
- UniProt
- A9JQL9
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dehydrosqualene synthase (EC 2.5.1.-) | protein | 284 | 74% helix, 0% strand | A9JQL9 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 537 | 0.75 | 0.83 | 53 | empty |
| 2 | 71 | 0.36 | 0.77 | 16 | empty |
| 3 | 69 | 0.31 | 0.74 | 12 | empty |
Compared structures
- 2ZCO · Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus… · the same entry in another collection · chain A against A, TM-score 1.00
- A9JQL9 · AlphaFold monomer V2.0 prediction for 4,4'-diapophytoene synthase (A9JQL9) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A9JQL9
- Elsewhere: RCSB PDB 2ZCO · PDBe 2ZCO · UniProt A9JQL9
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