MolNFT v1 · #56291 · protein

Crystal structure of mouse SKD1/VPS4B apo-form

2ZAM · Vacuolar protein sorting-associating protein 4B: “Crystal structure of mouse SKD1/VPS4B apo-form”. X-ray diffraction, 3 pockets (best druggability 0.70). MolNFT v1 #56291 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2ZAM
Type: protein
Length: 308 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Vacuolar protein sorting-associating protein 4B
UniProt: P46467
Pockets: 3 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vacuolar protein sorting-associating protein 4B	protein	308	40% helix, 18% strand	P46467

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	256	0.70	0.85	26	empty
2	102	0.48	0.80	21	empty
3	96	0.42	0.78	17	empty

Compared structures

2ZAM · Crystal structure of mouse SKD1/VPS4B apo-form · the same entry in another collection · chain A against A, TM-score 1.00
P46467 · AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 4B… · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P46467
Elsewhere: RCSB PDB 2ZAM · PDBe 2ZAM · UniProt P46467

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