MolNFT v1 · #56138 · protein
Solution structure of the tir domain of human MYD88
2Z5V · Myeloid differentiation primary response protein MYD88: “Solution structure of the tir domain of human MYD88”. Solution nmr, 2 pockets (best druggability 0.53). MolNFT v1 #56138 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 2Z5V
- Type
- protein
- Length
- 141 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Myeloid differentiation primary response protein MYD88
- UniProt
- Q99836
- Pockets
- 2 · best druggability 0.53
Structure
solution nmr · 1 distinct chain · 28% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myeloid differentiation primary response protein MYD88 | protein | 141 | 28% helix, 13% strand | Q99836 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 170 | 0.53 | 0.79 | 28 | empty |
| 2 | 57 | 0.32 | 0.77 | 16 | empty |
Compared structures
- 2Z5V · Solution structure of the TIR domain of human MyD88 · the same entry in another collection · chain A against A, TM-score 1.00
- Q99836 · AlphaFold monomer V2.0 prediction for myeloid differentiation primary response protein… · a predicted model of the same protein · chain A against A, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99836
- Elsewhere: RCSB PDB 2Z5V · PDBe 2Z5V · UniProt Q99836
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