MolNFT v1 · #56120 · protein
Human ubiquitin-conjugating enzyme E2 H
2Z5D: “Human ubiquitin-conjugating enzyme E2 H”. X-ray diffraction, 1 ligand (NA), 1 pocket (best druggability 0.70). MolNFT v1 #56120 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2Z5D
- Type
- protein
- Length
- 303 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin-conjugating enzyme E2 H
- EC
- 6.3.2.19
- UniProt
- P62256
- Ligands
- NA
- Pockets
- 1 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) | protein | 152 | 41% helix, 18% strand | P62256 |
| B | Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) | protein | 151 | 42% helix, 19% strand | P62256 |
Ligands and binding sites
- NA · Sodium ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 488 | 0.70 | 0.80 | 48 | empty |
Interfaces
1 interface between chains.
- A–B · 497 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62256
- Elsewhere: RCSB PDB 2Z5D · PDBe 2Z5D · UniProt P62256
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.