MolNFT v1 · #55931 · protein
Crystal structure of phosphoribosylaminoimidazole- succinocarboxamide synthase with ADP from methanocaldococcus jannaschii
2YZL · Phosphoribosylaminoimidazole-succinocarboxamide synthase: “Crystal structure of phosphoribosylaminoimidazole- succinocarboxamide synthase with ADP from…”. X-ray diffraction, 2 ligands (ADP, SO4), 2 pockets (best druggability 0.72).…
- PDB
- 2YZL
- Type
- protein
- Length
- 238 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- EC
- 6.3.2.6
- UniProt
- Q58987
- Ligands
- ADP, SO4
- Pockets
- 2 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | protein | 238 | 31% helix, 32% strand | Q58987 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 596 | 0.72 | 0.79 | 52 | SO4, ADP |
| 2 | 66 | 0.33 | 0.75 | 15 | empty |
Compared structures
- 2YZL · Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase with ADP… · the same entry in another collection · chain A against A, TM-score 1.00
- Q58987 · AlphaFold monomer V2.0 prediction for phosphoribosylaminoimidazole- succinocarboxamide… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q58987
- Elsewhere: RCSB PDB 2YZL · PDBe 2YZL · UniProt Q58987
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