MolNFT v1 · #55542 · protein

Wzi, an outer membrane protein involved in group 1 capsule assembly in escherichia COLI, is a carbohydrate binding beta-barrel

2YNK: “Wzi, an outer membrane protein involved in group 1 capsule assembly in escherichia COLI, is a carbohydrate…”. X-ray diffraction, 1 ligand (D12), 4 pockets (best druggability 0.87). MolNFT v1 #55542 on GenesisL1: 3D structure…

PDB: 2YNK
Type: protein
Length: 441 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Wzi
UniProt: Q8GNN6
Ligands: D12
Pockets: 4 · best druggability 0.87

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Wzi	protein	441	11% helix, 48% strand	Q8GNN6

Ligands and binding sites

D12 · Dodecane · ligand · 7 copies · chains A
OCT · N-octane · additive · 6 copies · chains A
HEX · Hexane · additive · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	772	0.87	0.90	66	empty
2	104	0.69	0.92	27	empty
3	140	0.63	0.86	36	empty
4	59	0.46	0.84	15	empty

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

2YNK · Wzi, an Outer Membrane Protein Involved in Group 1 Capsule Assembly in Escherichia coli… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8GNN6
Elsewhere: RCSB PDB 2YNK · PDBe 2YNK · UniProt Q8GNN6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.