MolNFT v1 · #5535 · protein + RNA

NMR structure of the complex between the third dsrbd from drosophila staufen and a RNA hairpin

1EKZ · Staufen double-stranded RNA binding domain: “NMR structure of the complex between the third dsrbd from drosophila staufen and a RNA hairpin”. Solution nmr, 2 pockets (best druggability 0.35). MolNFT v1 #5535 on GenesisL1: 3D…

PDB: 1EKZ
Type: protein + RNA
Length: 106 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Staufen double-stranded RNA binding domain; Maternal effect protein (staufen)
UniProt: P25159
Pockets: 2 · best druggability 0.35

Structure

solution nmr · 2 distinct chains · 29% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Staufen double-stranded RNA binding domain	rna	30	—	—
A	Maternal effect protein (staufen)	protein	76	29% helix, 18% strand	P25159

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	136	0.35	0.72	14	empty
2	88	0.33	0.74	19	empty

Interfaces

1 interface between chains.

B–A · 526 Å² buried · 13 hydrogen bonds · protein-nucleic

Compared structures

1EKZ · NMR structure of the complex between the third dsrbd from drosophila staufen and a RNA… · the same entry in another collection · chain B against B, TM-score 1.00
P25159 · AlphaFold monomer V2.0 prediction for maternal effect protein staufen (P25159) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25159
Elsewhere: RCSB PDB 1EKZ · PDBe 1EKZ · UniProt P25159

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.