MolNFT v1 · #55337 · protein
Crystal structure of the dimeric bame from E. COLI
2YH9 · Small protein a: “Crystal structure of the dimeric bame from E. COLI”. X-ray diffraction, 1 pocket (best druggability 0.69). MolNFT v1 #55337 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2YH9
- Type
- protein
- Length
- 201 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Small protein a
- UniProt
- P0A937
- Pockets
- 1 · best druggability 0.69
Structure
x-ray diffraction · 3 distinct chains · 12% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Small protein a | protein | 66 | 12% helix, 33% strand | P0A937 |
| B | Small protein a | protein | 68 | 12% helix, 26% strand | P0A937 |
| C | Small protein a | protein | 67 | 12% helix, 30% strand | P0A937 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 785 | 0.69 | 0.76 | 58 | empty |
Interfaces
3 interfaces between chains.
- A–C · 1798 Ų buried · 26 hydrogen bonds · protein-protein
- B–C · 853 Ų buried · 9 hydrogen bonds · protein-protein
- A–B · 345 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2YH9 · Crystal structure of the dimeric BamE from E. coli · the same entry in another collection · chain A against A, TM-score 1.00
- P0A937 · AlphaFold monomer V2.0 prediction for outer membrane protein assembly factor bame (P0A937) · a predicted model of the same protein · chain A against A, TM-score 0.42
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A937
- Elsewhere: RCSB PDB 2YH9 · PDBe 2YH9 · UniProt P0A937
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