MolNFT v1 · #55082 · protein

Crystal structure of cis-biphenyl-2,3-dihydrodiol-2,3- dehydrogenase (BPHB)FROM pandoraea pnomenusa strain B-356.

2Y93 · Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase: “Crystal structure of cis-biphenyl-2,3-dihydrodiol-2,3- dehydrogenase (BPHB)FROM pandoraea pnomenusa strain…”. X-ray diffraction, 3 pockets (best druggability 0.76). MolNFT v1 #55082…

PDB: 2Y93
Type: protein
Length: 536 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
EC: 1.3.1.56
UniProt: Q46381
Pockets: 3 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC 1.3.1.56)	protein	268	46% helix, 13% strand	Q46381

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	620	0.76	0.82	56	empty
2	592	0.75	0.82	58	empty
3	126	0.43	0.76	26	empty

Interfaces

1 interface between chains.

A–B · 2085 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

2Y93 · Crystal Structure of cis-Biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)from Pandoraea… · the same entry in another collection · chain A against A, TM-score 1.00
Q46381 · AlphaFold monomer V2.0 prediction for cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase… · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q46381
Elsewhere: RCSB PDB 2Y93 · PDBe 2Y93 · UniProt Q46381

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