MolNFT v1 · #55036 · protein
Structure of N-terminal domain of candida albicans ALS9-2 in complex with human fibrinogen gamma peptide
2Y7L · Agglutinin-like ALS9 protein: “Structure of N-terminal domain of candida albicans ALS9-2 in complex with human fibrinogen gamma peptide”. X-ray diffraction, 2 pockets (best druggability 0.60). MolNFT v1 #55036 on GenesisL1: 3D…
- PDB
- 2Y7L
- Type
- protein
- Length
- 319 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Agglutinin-like ALS9 protein; Fibrinogen gamma chain, isoform CRA_A
- UniProt
- Q5A8T1, D3DP16
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 56% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Agglutinin-like ALS9 protein | protein | 312 | 3% helix, 56% strand | Q5A8T1 |
| B | Fibrinogen gamma chain, isoform CRA_A | protein | 7 | 0% helix, 57% strand | D3DP16 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 193 | 0.60 | 0.81 | 28 | empty |
| 2 | 90 | 0.34 | 0.74 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 573 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 2Y7L · Structure of N-terminal domain of Candida albicans Als9-2 in complex with human… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5A8T1
- Every structure of UniProt D3DP16
- Elsewhere: RCSB PDB 2Y7L · PDBe 2Y7L · UniProt Q5A8T1 · UniProt D3DP16
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