MolNFT v1 · #54718 · protein
A widespread family of bacterial cell wall assembly proteins
2XXP · CPS2A: “A widespread family of bacterial cell wall assembly proteins”. X-ray diffraction, 1 ligand (DSL), 4 pockets (best druggability 0.87). MolNFT v1 #54718 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2XXP
- Type
- protein
- Length
- 374 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CPS2A
- UniProt
- Q9ZII9
- Ligands
- DSL
- Pockets
- 4 · best druggability 0.87
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CPS2A | protein | 374 | 39% helix, 27% strand | Q9ZII9 |
Ligands and binding sites
- DSL · Mono-trans, octa-cis decaprenyl-phosphate · ligand · chains A
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 808 | 0.87 | 0.89 | 60 | DSL |
| 2 | 157 | 0.50 | 0.79 | 21 | PEG |
| 3 | 51 | 0.49 | 0.86 | 17 | empty |
| 4 | 82 | 0.37 | 0.76 | 14 | empty |
Compared structures
- 2XXP · A widespread family of bacterial cell wall assembly proteins · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ZII9
- Elsewhere: RCSB PDB 2XXP · PDBe 2XXP · UniProt Q9ZII9
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