MolNFT v1 · #54444 · protein

Structure of the tandem SH2 domains from antonospora locustae transcription elongation factor SPT6

2XP1: “Structure of the tandem SH2 domains from antonospora locustae transcription elongation factor SPT6”. X-ray diffraction, 2 ligands (SO4, CL), 1 pocket (best druggability 0.41). MolNFT v1 #54444 on GenesisL1: 3D structure, binding…

PDB: 2XP1
Type: protein
Length: 175 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SPT6
Ligands: SO4, CL
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SPT6	protein	175	28% helix, 34% strand	—

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.41	0.79	19	empty

Compared structures

2XP1 · Structure of the tandem SH2 domains from Antonospora locustae transcription elongation… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2XP1 · PDBe 2XP1

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