MolNFT v1 · #53781 · protein

Yersinia pestis plasminogen activator pla (native)

2X55 · COAGULASE/FIBRINOLYSIN: “Yersinia pestis plasminogen activator pla (native)”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.77). MolNFT v1 #53781 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2X55
Type: protein
Length: 274 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: COAGULASE/FIBRINOLYSIN
EC: 3.4.23.48
UniProt: P17811
Ligands: SO4
Pockets: 2 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 78% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	COAGULASE/FIBRINOLYSIN (EC 3.4.23.48)	protein	274	2% helix, 78% strand	P17811

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A
C8E · (hydroxyethyloxy)tri(ethyloxy)octane · additive · 23 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	313	0.77	0.89	47	empty
2	154	0.52	0.79	25	C8E

Compared structures

2X55 · Yersinia Pestis Plasminogen Activator Pla (Native) · the same entry in another collection · chain A against A, TM-score 1.00
P17811 · AlphaFold monomer V2.0 prediction for COAGULASE/FIBRINOLYSIN (P17811) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P17811
Elsewhere: RCSB PDB 2X55 · PDBe 2X55 · UniProt P17811

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