MolNFT v1 · #53378 · protein

Head domain of porcine adenovirus type 4 nadc-1 isolate fibre

2WST · Putative fiber protein: “Head domain of porcine adenovirus type 4 nadc-1 isolate fibre”. X-ray diffraction, 7 pockets (best druggability 0.78). MolNFT v1 #53378 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2WST
Type: protein
Length: 1,056 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative fiber protein
UniProt: Q83467
Pockets: 7 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F	Putative fiber protein	protein	176	6% helix, 45% strand	Q83467

Pockets

7 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	435	0.78	0.86	47	empty
2	391	0.77	0.86	38	empty
3	293	0.66	0.82	37	empty
4	376	0.62	0.78	42	empty
5	215	0.60	0.81	44	empty

Interfaces

9 interfaces between chains.

B–C · 1029 Å² buried · 12 hydrogen bonds · protein-protein
A–B · 1006 Å² buried · 11 hydrogen bonds · protein-protein
D–F · 1001 Å² buried · 13 hydrogen bonds · protein-protein
D–E · 994 Å² buried · 15 hydrogen bonds · protein-protein
E–F · 994 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

2WST · Head domain of porcine adenovirus type 4 NADC-1 isolate fibre · the same entry in another collection · chain D against D, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q83467
Elsewhere: RCSB PDB 2WST · PDBe 2WST · UniProt Q83467

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