MolNFT v1 · #53243 · protein
Nucleotide-free form of S. pombe GET3
2WOO · ATPase GET3: “Nucleotide-free form of S. pombe GET3”. X-ray diffraction, 1 ligand (ZN), 20 pockets (best druggability 0.75). MolNFT v1 #53243 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2WOO
- Type
- protein
- Length
- 1,818 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATPase GET3
- EC
- 3.6.3.16
- UniProt
- Q9P7F8
- Ligands
- ZN
- Pockets
- 20 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | ATPase GET3 (EC 3.6.3.16) | protein | 303 | 49% helix, 15% strand | Q9P7F8 |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 477 | 0.75 | 0.84 | 37 | empty |
| 2 | 525 | 0.75 | 0.83 | 50 | empty |
| 3 | 465 | 0.74 | 0.83 | 41 | empty |
| 4 | 599 | 0.73 | 0.81 | 41 | empty |
| 5 | 518 | 0.73 | 0.82 | 47 | empty |
Interfaces
12 interfaces between chains.
- A–B · 1029 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 1001 Ų buried · 9 hydrogen bonds · protein-protein
- E–F · 963 Ų buried · 6 hydrogen bonds · protein-protein
- C–E · 516 Ų buried · 7 hydrogen bonds · protein-protein
- D–F · 512 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9P7F8
- Elsewhere: RCSB PDB 2WOO · PDBe 2WOO · UniProt Q9P7F8
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