MolNFT v1 · #53139 · protein

Potassium channel from magnetospirillum magnetotacticum

2WLO: “Potassium channel from magnetospirillum magnetotacticum”. X-ray diffraction, 1 ligand (K), 5 pockets (best druggability 0.75). MolNFT v1 #53139 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2WLO
Type: protein
Length: 555 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Potassium channel
Ligands: K
Pockets: 5 · best druggability 0.75

Structure

x-ray diffraction · 2 distinct chains · 31% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Potassium channel	protein	283	31% helix, 33% strand	—
B	Potassium channel	protein	272	32% helix, 33% strand	—

Ligands and binding sites

K · Potassium ion · metal · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	476	0.75	0.84	46	empty
2	492	0.66	0.77	47	empty
3	109	0.42	0.77	18	empty
4	140	0.39	0.74	20	empty
5	61	0.31	0.75	13	empty

Interfaces

1 interface between chains.

A–B · 2745 Å² buried · 31 hydrogen bonds · protein-protein

Compared structures

2WLO · Potassium channel from magnetospirillum magnetotacticum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2WLO · PDBe 2WLO

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