MolNFT v1 · #52780 · protein

2.1 resolution structure of the C-terminal domain of the human adenovirus 5 ssdna binding protein

2WB0 · E2A DNA-binding protein: “2.1 resolution structure of the C-terminal domain of the human adenovirus 5 ssdna binding protein”. X-ray diffraction, 1 ligand (ZN), 3 pockets (best druggability 0.58). MolNFT v1 #52780 on GenesisL1: 3D…

PDB: 2WB0
Type: protein
Length: 314 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E2A DNA-binding protein
UniProt: Q2KS06
Ligands: ZN
Pockets: 3 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	E2A DNA-binding protein	protein	314	34% helix, 15% strand	Q2KS06

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	316	0.58	0.77	41	empty
2	148	0.51	0.78	18	empty
3	110	0.38	0.74	18	empty

Compared structures

2WB0 · 2.1 resolution structure of the C-terminal domain of the human adenovirus 5 ssDNA binding… · the same entry in another collection · chain X against X, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2KS06
Elsewhere: RCSB PDB 2WB0 · PDBe 2WB0 · UniProt Q2KS06

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