MolNFT v1 · #52672 · protein
Trypanosoma brucei ctps - glutaminase domain with bound acivicin
2W7T · Putative cytidine triphosphate synthase: “Trypanosoma brucei ctps - glutaminase domain with bound acivicin”. X-ray diffraction, 1 ligand (CL), 1 pocket (best druggability 0.39). MolNFT v1 #52672 on GenesisL1: 3D structure, binding…
- PDB
- 2W7T
- Type
- protein
- Length
- 264 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative cytidine triphosphate synthase
- EC
- 6.3.4.2
- UniProt
- Q4GZ95
- Ligands
- CL
- Pockets
- 1 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative cytidine triphosphate synthase (EC 6.3.4.2) | protein | 264 | 35% helix, 25% strand | Q4GZ95 |
Ligands and binding sites
- CL · Chloride ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 74 | 0.39 | 0.79 | 22 | CL |
Modifications
Observed in the structure: 1 modified (nonstandard).
Compared structures
- 2W7T · Trypanosoma brucei CTPS - glutaminase domain with bound acivicin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4GZ95
- Elsewhere: RCSB PDB 2W7T · PDBe 2W7T · UniProt Q4GZ95
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