MolNFT v1 · #52395 · protein
Crystal structure of the major allergen from fire ant venom, sol I 3
2VZN · Venom allergen 3: “Crystal structure of the major allergen from fire ant venom, sol I 3”. X-ray diffraction, 4 pockets (best druggability 0.64). MolNFT v1 #52395 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2VZN
- Type
- protein
- Length
- 419 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Venom allergen 3
- UniProt
- P35778
- Pockets
- 4 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Venom allergen 3 | protein | 216 | 32% helix, 16% strand | P35778 |
| B | Venom allergen 3 | protein | 203 | 33% helix, 18% strand | P35778 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 427 | 0.64 | 0.77 | 47 | empty |
| 2 | 390 | 0.61 | 0.77 | 42 | empty |
| 3 | 128 | 0.39 | 0.74 | 16 | empty |
| 4 | 88 | 0.33 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 642 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35778
- Elsewhere: RCSB PDB 2VZN · PDBe 2VZN · UniProt P35778
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