MolNFT v1 · #52240 · protein

Crystal structure of glycogen debranching exzyme trex from sulfolobus solfatarius

2VUY · Glycogen operon protein glgx: “Crystal structure of glycogen debranching exzyme trex from sulfolobus solfatarius”. X-ray diffraction, 19 pockets (best druggability 0.78). MolNFT v1 #52240 on GenesisL1: 3D structure, binding sites…

PDB: 2VUY
Type: protein
Length: 1,424 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycogen operon protein glgx
EC: 3.2.1.-
UniProt: P95868
Pockets: 19 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 26% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycogen operon protein glgx (EC 3.2.1.-)	protein	713	26% helix, 21% strand	P95868
B	Glycogen operon protein glgx (EC 3.2.1.-)	protein	711	26% helix, 21% strand	P95868

Pockets

19 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1021	0.78	0.80	77	empty
2	928	0.78	0.80	69	empty
3	530	0.66	0.77	52	empty
4	554	0.66	0.77	53	empty
5	234	0.57	0.78	24	empty

Interfaces

1 interface between chains.

A–B · 1367 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

2VUY · Crystal structure of Glycogen Debranching exzyme TreX from Sulfolobus solfatarius · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P95868
Elsewhere: RCSB PDB 2VUY · PDBe 2VUY · UniProt P95868

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