MolNFT v1 · #52137 · protein
Structural analysis of homodimeric staphylococcal aureus esxa
2VRZ · Virulence factor esxa: “Structural analysis of homodimeric staphylococcal aureus esxa”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #52137 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2VRZ
- Type
- protein
- Length
- 183 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Virulence factor esxa
- UniProt
- Q99WU4
- Ligands
- ZN
Structure
x-ray diffraction · 2 distinct chains · 85% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Virulence factor esxa | protein | 98 | 84% helix, 1% strand | Q99WU4 |
| B | Virulence factor esxa | protein | 85 | 86% helix, 1% strand | Q99WU4 |
Ligands and binding sites
- ZN · Zinc ion · metal · 7 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 1923 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 2VRZ · Structural analysis of homodimeric staphylococcal aureus EsxA · the same entry in another collection · chain A against A, TM-score 1.00
- Q99WU4 · AlphaFold monomer V2.0 prediction for type VII secretion system extracellular protein a… · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99WU4
- Elsewhere: RCSB PDB 2VRZ · PDBe 2VRZ · UniProt Q99WU4
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