MolNFT v1 · #51925 · protein
Crystal structure of barley thioredoxin H isoform 2 in the oxidized state
2VLT · Thioredoxin H isoform 2.: “Crystal structure of barley thioredoxin H isoform 2 in the oxidized state”. X-ray diffraction, 1 pocket (best druggability 0.65). MolNFT v1 #51925 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2VLT
- Type
- protein
- Length
- 221 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thioredoxin H isoform 2.
- EC
- 1.8.1.9
- UniProt
- Q7XZK2
- Pockets
- 1 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thioredoxin H isoform 2. (EC 1.8.1.9) | protein | 111 | 42% helix, 25% strand | Q7XZK2 |
| B | Thioredoxin H isoform 2. (EC 1.8.1.9) | protein | 110 | 42% helix, 26% strand | Q7XZK2 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 369 | 0.65 | 0.80 | 47 | empty |
Interfaces
1 interface between chains.
- A–B · 202 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 2VLT · Crystal structure of barley thioredoxin h isoform 2 in the oxidized state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7XZK2
- Elsewhere: RCSB PDB 2VLT · PDBe 2VLT · UniProt Q7XZK2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.