MolNFT v1 · #51834 · protein

Shigella flexneri mxic

2VJ5 · Protein mxic: “Shigella flexneri mxic”. X-ray diffraction, 6 pockets (best druggability 0.71). MolNFT v1 #51834 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2VJ5
Type: protein
Length: 566 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein mxic
UniProt: Q04640
Pockets: 6 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein mxic	protein	283	62% helix, 0% strand	Q04640

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1033	0.71	0.75	54	empty
2	82	0.65	0.91	18	empty
3	70	0.37	0.77	13	empty
4	57	0.31	0.76	13	empty
5	62	0.30	0.75	14	empty

Interfaces

1 interface between chains.

A–B · 486 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

2VJ5 · Shigella flexneri MxiC · the same entry in another collection · chain A against A, TM-score 1.00
Q04640 · AlphaFold monomer V2.0 prediction for protein mxic (Q04640) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q04640
Elsewhere: RCSB PDB 2VJ5 · PDBe 2VJ5 · UniProt Q04640

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