MolNFT v1 · #51811 · protein

PSPF1-275-mg-AMP

2VII · Psp operon transcriptional activator: “PSPF1-275-mg-AMP”. X-ray diffraction, 2 ligands (AMP, MG), 2 pockets (best druggability 0.43). MolNFT v1 #51811 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2VII
Type: protein
Length: 247 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Psp operon transcriptional activator
UniProt: P37344
Ligands: AMP, MG
Pockets: 2 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Psp operon transcriptional activator	protein	247	48% helix, 14% strand	P37344

Ligands and binding sites

AMP · Adenosine monophosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	124	0.43	0.76	23	AMP, MG
2	67	0.37	0.78	15	empty

Compared structures

2VII · PspF1-275-Mg-AMP · the same entry in another collection · chain A against A, TM-score 1.00
P37344 · AlphaFold monomer V2.0 prediction for psp operon transcriptional activator (P37344) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P37344
Elsewhere: RCSB PDB 2VII · PDBe 2VII · UniProt P37344

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