MolNFT v1 · #51740 · protein

Crystal structure of the C-terminal region of human iaspp

2VGE · Rela-associated inhibitor: “Crystal structure of the C-terminal region of human iaspp”. X-ray diffraction, 1 pocket (best druggability 0.46). MolNFT v1 #51740 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2VGE
Type: protein
Length: 207 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Rela-associated inhibitor
UniProt: Q8WUF5
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rela-associated inhibitor	protein	207	36% helix, 13% strand	Q8WUF5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	131	0.46	0.77	20	empty

Compared structures

2VGE · Crystal structure of the C-terminal region of human iASPP · the same entry in another collection · chain A against A, TM-score 1.00
Q8WUF5 · AlphaFold monomer V2.0 prediction for rela-associated inhibitor (Q8WUF5) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WUF5
Elsewhere: RCSB PDB 2VGE · PDBe 2VGE · UniProt Q8WUF5

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