MolNFT v1 · #51594 · protein
Ricin a-chain (recombinant) E177D mutant with a bound acetate
2VC3 · Ricin a chain: “Ricin a-chain (recombinant) E177D mutant with a bound acetate”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.56). MolNFT v1 #51594 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2VC3
- Type
- protein
- Length
- 263 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ricin a chain
- EC
- 3.2.2.22
- UniProt
- P02879
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ricin a chain (EC 3.2.2.22) | protein | 263 | 41% helix, 22% strand | P02879 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.56 | 0.83 | 24 | empty |
| 2 | 59 | 0.39 | 0.79 | 12 | empty |
| 3 | 61 | 0.38 | 0.79 | 18 | ACT |
Compared structures
- 2VC3 · Ricin A-Chain (Recombinant) E177D Mutant with a bound acetate · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02879
- Elsewhere: RCSB PDB 2VC3 · PDBe 2VC3 · UniProt P02879
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.