MolNFT v1 · #51224 · protein

Kinesin 16B phox-homology domain (KIF16B)

2V14 · Kinesin-like motor protein C20ORF23: “Kinesin 16B phox-homology domain (KIF16B)”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #51224 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2V14
Type: protein
Length: 134 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Kinesin-like motor protein C20ORF23
UniProt: Q96L93
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Kinesin-like motor protein C20ORF23	protein	134	40% helix, 22% strand	Q96L93

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.37	0.78	13	empty

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

2V14 · Kinesin 16B Phox-homology domain (KIF16B) · the same entry in another collection · chain A against A, TM-score 1.00
Q96L93 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF16B (Q96L93) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96L93
Elsewhere: RCSB PDB 2V14 · PDBe 2V14 · UniProt Q96L93

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