MolNFT v1 · #51033 · protein

Structure of yjht

2UVK: “Structure of yjht”. X-ray diffraction, 10 pockets (best druggability 0.78). MolNFT v1 #51033 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2UVK
Type: protein
Length: 691 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Yjht
UniProt: P39371
Pockets: 10 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 12% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Yjht	protein	342	12% helix, 42% strand	P39371
B	Yjht	protein	349	12% helix, 42% strand	P39371

Pockets

10 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	454	0.78	0.86	43	empty
2	460	0.77	0.86	37	empty
3	310	0.73	0.85	50	empty
4	112	0.68	0.90	23	empty
5	531	0.66	0.77	46	empty

Interfaces

1 interface between chains.

A–B · 1332 Å² buried · 30 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

2UVK · Structure of YjhT · the same entry in another collection · chain A against A, TM-score 1.00
P39371 · AlphaFold monomer V2.0 prediction for N-acetylneuraminate epimerase (P39371) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39371
Elsewhere: RCSB PDB 2UVK · PDBe 2UVK · UniProt P39371

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