MolNFT v1 · #51013 · protein
2.75 ångström structure of the D347G D348G mutant structure of sapporo virus rdrp polymerase
2UUW · RNA-directed RNA polymerase: “2.75 ångström structure of the D347G D348G mutant structure of sapporo virus rdrp polymerase”. X-ray diffraction, 4 pockets (best druggability 0.62). MolNFT v1 #51013 on GenesisL1: 3D structure, binding…
- PDB
- 2UUW
- Type
- protein
- Length
- 490 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-directed RNA polymerase
- EC
- 2.7.7.48
- UniProt
- Q69014
- Pockets
- 4 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA-directed RNA polymerase (EC 2.7.7.48) | protein | 490 | 43% helix, 17% strand | Q69014 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 450 | 0.62 | 0.76 | 37 | empty |
| 2 | 361 | 0.56 | 0.75 | 55 | empty |
| 3 | 108 | 0.43 | 0.78 | 22 | empty |
| 4 | 104 | 0.34 | 0.73 | 14 | empty |
Compared structures
- 2UUW · 2.75 angstrom structure of the D347G D348G mutant structure of Sapporo Virus RdRp… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q69014
- Elsewhere: RCSB PDB 2UUW · PDBe 2UUW · UniProt Q69014
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