MolNFT v1 · #5092 · protein
Human serum albumin complexed with octadecanoic acid (stearic acid)
1E7I: “Human serum albumin complexed with octadecanoic acid (stearic acid)”. X-ray diffraction, 1 ligand (STE), 7 pockets (best druggability 0.89). MolNFT v1 #5092 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1E7I
- Type
- protein
- Length
- 582 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serum albumin
- UniProt
- P02768
- Ligands
- STE
- Pockets
- 7 · best druggability 0.89
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serum albumin | protein | 582 | 73% helix, 0% strand | P02768 |
Ligands and binding sites
- STE · Stearic acid · ligand · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1116 | 0.89 | 0.91 | 108 | STE |
| 2 | 262 | 0.79 | 0.91 | 34 | STE |
| 3 | 366 | 0.73 | 0.84 | 30 | STE |
| 4 | 287 | 0.71 | 0.84 | 37 | STE |
| 5 | 105 | 0.59 | 0.86 | 16 | STE |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02768
- Elsewhere: RCSB PDB 1E7I · PDBe 1E7I · UniProt P02768
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.