MolNFT v1 · #50761 · protein
Solution structure of the SH2 domain of csk in complex with a phosphopeptide from cbp
2RSY · Tyrosine-protein kinase csk: “Solution structure of the SH2 domain of csk in complex with a phosphopeptide from cbp”. Solution nmr. MolNFT v1 #50761 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2RSY
- Type
- protein
- Length
- 137 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine-protein kinase csk; Phosphoprotein associated with glycosphingolipid-enriched…
- EC
- 2.7.10.2
- UniProt
- P32577, Q9JM80
Structure
solution nmr · 2 distinct chains · 17% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase csk (EC 2.7.10.2) | protein | 99 | 17% helix, 29% strand | P32577 |
| B | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 | protein | 38 | 16% helix, 0% strand | Q9JM80 |
Interfaces
1 interface between chains.
- A–B · 1003 Ų buried · 17 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide, 1 modified (disulfide, phosphorylation).
Compared structures
- 2RSY · Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp · the same entry in another collection · chain A against A, TM-score 1.00
- P32577 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase csk (P32577) · a predicted model of the same protein · chain A against A, TM-score 0.92
- Q9JM80 · AlphaFold monomer V2.0 prediction for phosphoprotein associated with… · a predicted model of the same protein · chain B against A, TM-score 0.41
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32577
- Every structure of UniProt Q9JM80
- Elsewhere: RCSB PDB 2RSY · PDBe 2RSY · UniProt P32577 · UniProt Q9JM80
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