MolNFT v1 · #50754 · protein
Structure of the aspartic protease from rous sarcoma retrovirus refined at 2 ångströms resolution
2RSP · Rsv protease: “Structure of the aspartic protease from rous sarcoma retrovirus refined at 2 ångströms resolution”. X-ray diffraction, 2 pockets (best druggability 0.57). MolNFT v1 #50754 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2RSP
- Type
- protein
- Length
- 228 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Rsv protease
- UniProt
- P03322
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rsv protease | protein | 115 | 5% helix, 42% strand | P03322 |
| B | Rsv protease | protein | 113 | 6% helix, 42% strand | P03322 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 376 | 0.57 | 0.75 | 33 | empty |
| 2 | 65 | 0.32 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1548 Ų buried · 46 hydrogen bonds · protein-protein
Compared structures
- 2RSP · Structure of the aspartic protease from rous sarcoma retrovirus refined at 2 ångströms… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03322
- Elsewhere: RCSB PDB 2RSP · PDBe 2RSP · UniProt P03322
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