MolNFT v1 · #50713 · protein

Solution structure of calponin homology domain of IQGAP1

2RR8 · IQGAP1 protein: “Solution structure of calponin homology domain of IQGAP1”. Solution nmr, 3 pockets (best druggability 0.41). MolNFT v1 #50713 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2RR8
Type: protein
Length: 190 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: IQGAP1 protein
UniProt: Q6P1N4
Pockets: 3 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 48% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	IQGAP1 protein	protein	190	48% helix, 0% strand	Q6P1N4

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.41	0.79	15	empty
2	60	0.31	0.76	13	empty
3	53	0.30	0.76	15	empty

Compared structures

2RR8 · Solution structure of calponin homology domain of IQGAP1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6P1N4
Elsewhere: RCSB PDB 2RR8 · PDBe 2RR8 · UniProt Q6P1N4

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