MolNFT v1 · #50667 · protein
Solution structure of a sumo-interacting motif of MBD1-containing chromatin-associated factor 1 bound to sumo-3
2RPQ · Small ubiquitin-related modifier 2: “Solution structure of a sumo-interacting motif of MBD1-containing chromatin-associated factor 1 bound to…”. Solution nmr, 1 pocket (best druggability 0.46). MolNFT v1 #50667 on GenesisL1: 3D…
- PDB
- 2RPQ
- Type
- protein
- Length
- 104 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Small ubiquitin-related modifier 2; Activating transcription factor 7-interacting protein…
- UniProt
- P61956, Q6VMQ6
- Pockets
- 1 · best druggability 0.46
Structure
solution nmr · 2 distinct chains · 12% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Small ubiquitin-related modifier 2 | protein | 93 | 13% helix, 33% strand | P61956 |
| B | Activating transcription factor 7-interacting protein 1 | protein | 11 | 0% helix, 18% strand | Q6VMQ6 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 116 | 0.46 | 0.79 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 688 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 2RPQ · Solution Structure of a SUMO-interacting motif of MBD1-containing chromatin-associated… · the same entry in another collection · chain A against A, TM-score 1.00
- P61956 · AlphaFold monomer V2.0 prediction for small ubiquitin-related modifier 2 (P61956) · a predicted model of the same protein · chain A against A, TM-score 0.74
- Q6VMQ6 · AlphaFold monomer V2.0 prediction for activating transcription factor 7-interacting… · a predicted model of the same protein · chain B against A, TM-score 0.27
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61956
- Every structure of UniProt Q6VMQ6
- Elsewhere: RCSB PDB 2RPQ · PDBe 2RPQ · UniProt P61956 · UniProt Q6VMQ6
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