MolNFT v1 · #50639 · protein

Solution structure of MAGI4, a spider toxin from macrothele gigas

2ROO · Neurotoxin magi-4: “Solution structure of MAGI4, a spider toxin from macrothele gigas”. Solution nmr, 1 pocket (best druggability 0.35). MolNFT v1 #50639 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2ROO
Type: protein
Length: 43 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Neurotoxin magi-4
UniProt: P83560
Pockets: 1 · best druggability 0.35

Structure

solution nmr · 1 distinct chain · 14% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Neurotoxin magi-4	protein	43	14% helix, 26% strand	P83560

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.35	0.78	16	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

2ROO · Solution structure of Magi4, a spider toxin from Macrothele gigas · the same entry in another collection · chain A against A, TM-score 1.00
P83560 · AlphaFold monomer V2.0 prediction for delta-hexatoxin-MG1A (P83560) · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P83560
Elsewhere: RCSB PDB 2ROO · PDBe 2ROO · UniProt P83560

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