MolNFT v1 · #50631 · protein
Solution structure of mcl-1 complexed with noxaa
2ROD · Induced myeloid leukemia cell differentiation protein mcl-1…: “Solution structure of mcl-1 complexed with noxaa”. Solution nmr. MolNFT v1 #50631 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2ROD
- Type
- protein
- Length
- 189 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Induced myeloid leukemia cell differentiation protein mcl-1 homolog; Noxa
- UniProt
- P97287, Q9JM54
Structure
solution nmr · 2 distinct chains · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Induced myeloid leukemia cell differentiation protein mcl-1 homolog | protein | 162 | 69% helix, 0% strand | P97287 |
| B | Noxa | protein | 27 | 67% helix, 0% strand | Q9JM54 |
Interfaces
1 interface between chains.
- A–B · 1133 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 2ROD · Solution Structure of MCL-1 Complexed with NoxaA · the same entry in another collection · chain A against A, TM-score 1.00
- P97287 · AlphaFold monomer V2.0 prediction for induced myeloid leukemia cell differentiation… · a predicted model of the same protein · chain A against A, TM-score 0.89
- Q9JM54 · AlphaFold monomer V2.0 prediction for phorbol-12-myristate-13-acetate-induced protein 1… · a predicted model of the same protein · chain B against A, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P97287
- Every structure of UniProt Q9JM54
- Elsewhere: RCSB PDB 2ROD · PDBe 2ROD · UniProt P97287 · UniProt Q9JM54
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