MolNFT v1 · #50593 · RNA
Liquid crystal solution structure of the kissing complex formed by the apical loop of the HIV tar RNA and a high affinity RNA aptamer optimized by selex
2RN1 · RNA (5'- R(P*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)…: “Liquid crystal solution structure of the kissing complex formed by the apical loop of the HIV tar RNA and a…”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT…
- PDB
- 2RN1
- Type
- RNA
- Length
- 32 nucleotides
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA (5'- R(P*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)-3'); RNA (5'…
- Pockets
- 1 · best druggability 0.41
Structure
solution nmr · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA (5'- R(P*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)-3') | rna | 16 | — | — |
| B | RNA (5'- R(P*GP*CP*UP*GP*GP*UP*CP*CP*CP*AP*GP*AP*CP*AP*GP*C)-3') | rna | 16 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 140 | 0.41 | 0.76 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 487 Ų buried · 36 hydrogen bonds · nucleic-nucleic
Compared structures
- 2RN1 · Liquid crystal solution structure of the kissing complex formed by the apical loop of the… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2RN1 · PDBe 2RN1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.