MolNFT v1 · #50507 · protein

The crystal structure of a GLYOXALASE/BLEOMYCIN resistance PROTEIN/DIOXYGENASE superfamily member from vibrio splendidus 12B01

2RK9: “The crystal structure of a GLYOXALASE/BLEOMYCIN resistance PROTEIN/DIOXYGENASE superfamily member from vibrio…”. X-ray diffraction, 2 pockets (best druggability 0.51). MolNFT v1 #50507 on GenesisL1: 3D structure, binding sites and…

PDB: 2RK9
Type: protein
Length: 233 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GLYOXALASE/BLEOMYCIN resistance PROTEIN/DIOXYGENASE
UniProt: A3UM69
Pockets: 2 · best druggability 0.51

Structure

x-ray diffraction · 2 distinct chains · 24% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GLYOXALASE/BLEOMYCIN resistance PROTEIN/DIOXYGENASE	protein	116	25% helix, 47% strand	A3UM69
B	GLYOXALASE/BLEOMYCIN resistance PROTEIN/DIOXYGENASE	protein	117	24% helix, 48% strand	A3UM69

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	273	0.51	0.75	54	empty
2	66	0.28	0.73	18	empty

Interfaces

1 interface between chains.

A–B · 2105 Å² buried · 25 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

2RK9 · The crystal structure of a glyoxalase/bleomycin resistance protein/dioxygenase… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A3UM69
Elsewhere: RCSB PDB 2RK9 · PDBe 2RK9 · UniProt A3UM69

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