MolNFT v1 · #50403 · protein

Structure of apo anthocyanidin reductase from vitis vinifera

2RH8: “Structure of apo anthocyanidin reductase from vitis vinifera”. X-ray diffraction, 1 ligand (CL), 3 pockets (best druggability 0.54). MolNFT v1 #50403 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2RH8
Type: protein
Length: 312 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Anthocyanidin reductase
EC: 1.3.1.77
UniProt: Q5FB34
Ligands: CL
Pockets: 3 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Anthocyanidin reductase (EC 1.3.1.77)	protein	312	42% helix, 15% strand	Q5FB34

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	276	0.54	0.76	45	CL
2	120	0.47	0.78	17	empty
3	57	0.28	0.74	11	empty

Compared structures

2RH8 · Structure of apo anthocyanidin reductase from vitis vinifera · the same entry in another collection · chain A against A, TM-score 1.00
Q5FB34 · AlphaFold monomer V2.0 prediction for anthocyanidin reductase ((2S)-flavan-3-ol-forming)… · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5FB34
Elsewhere: RCSB PDB 2RH8 · PDBe 2RH8 · UniProt Q5FB34

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