MolNFT v1 · #50354 · protein

High resolution structure of L-methionine gamma-lyase from citrobacter freundii

2RFV: “High resolution structure of L-methionine gamma-lyase from citrobacter freundii”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.54). MolNFT v1 #50354 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2RFV
Type: protein
Length: 391 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methionine gamma-lyase
EC: 4.4.1.11
UniProt: Q84AR1
Ligands: CL
Pockets: 2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methionine gamma-lyase (EC 4.4.1.11)	protein	391	42% helix, 16% strand	Q84AR1

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	226	0.54	0.77	29	empty
2	121	0.47	0.79	32	empty

Modifications

Observed in the structure: 2 modified (cofactor, oxidation).

Compared structures

2RFV · High resolution structure of L-methionine gamma-lyase from Citrobacter freundii · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q84AR1
Elsewhere: RCSB PDB 2RFV · PDBe 2RFV · UniProt Q84AR1

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