MolNFT v1 · #50334 · protein

Crystal structure of the mouse TRPV6 ankyrin repeat domain

2RFA · Transient receptor potential cation channel subfamily V…: “Crystal structure of the mouse TRPV6 ankyrin repeat domain”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #50334 on GenesisL1: 3D structure, binding sites…

PDB: 2RFA
Type: protein
Length: 222 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transient receptor potential cation channel subfamily V member 6
UniProt: Q91WD2
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transient receptor potential cation channel subfamily V member 6	protein	222	52% helix, 0% strand	Q91WD2

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.36	0.76	16	empty

Compared structures

2RFA · Crystal structure of the mouse TRPV6 ankyrin repeat domain · the same entry in another collection · chain A against A, TM-score 1.00
Q91WD2 · AlphaFold monomer V2.0 prediction for transient receptor potential cation channel… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q91WD2
Elsewhere: RCSB PDB 2RFA · PDBe 2RFA · UniProt Q91WD2

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