MolNFT v1 · #50261 · protein
Crystal structure of tena homologue (HP1287) from helicobacter pylori
2RD3 · Transcriptional regulator: “Crystal structure of tena homologue (HP1287) from helicobacter pylori”. X-ray diffraction, 4 pockets (best druggability 0.75). MolNFT v1 #50261 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2RD3
- Type
- protein
- Length
- 439 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator
- EC
- 3.5.99.2
- UniProt
- O25874
- Pockets
- 4 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator (EC 3.5.99.2) | protein | 221 | 76% helix, 0% strand | O25874 |
| D | Transcriptional regulator (EC 3.5.99.2) | protein | 218 | 76% helix, 0% strand | O25874 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 237 | 0.75 | 0.89 | 33 | empty |
| 2 | 258 | 0.75 | 0.88 | 31 | empty |
| 3 | 144 | 0.50 | 0.79 | 26 | empty |
| 4 | 128 | 0.47 | 0.78 | 18 | empty |
Interfaces
1 interface between chains.
- A–D · 762 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 2RD3 · Crystal structure of TenA homologue (HP1287) from Helicobacter pylori · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O25874
- Elsewhere: RCSB PDB 2RD3 · PDBe 2RD3 · UniProt O25874
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