MolNFT v1 · #50219 · protein
Cytochrome C peroxidase in complex with cyclopentane-carboximidamide
2RBU: “Cytochrome C peroxidase in complex with cyclopentane-carboximidamide”. X-ray diffraction, 2 ligands (HEM, 273), 2 pockets (best druggability 0.81). MolNFT v1 #50219 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2RBU
- Type
- protein
- Length
- 292 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome C peroxidase
- EC
- 1.11.1.5
- UniProt
- A7A026
- Ligands
- HEM, 273
- Pockets
- 2 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Cytochrome C peroxidase (EC 1.11.1.5) | protein | 292 | 50% helix, 7% strand | A7A026 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains X
- 273 · cyclopentanecarboximidamide · ligand · chains X
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 473 | 0.81 | 0.88 | 58 | HEM, 273 |
| 2 | 91 | 0.39 | 0.77 | 20 | empty |
Compared structures
- 2RBU · Cytochrome C Peroxidase in complex with cyclopentane-carboximidamide · the same entry in another collection · chain X against X, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7A026
- Elsewhere: RCSB PDB 2RBU · PDBe 2RBU · UniProt A7A026
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.