MolNFT v1 · #50173 · protein
SO4 bound px-bar membrane remodeling unit of sorting nexin 9
2RAJ · Sorting nexin-9: “SO4 bound px-bar membrane remodeling unit of sorting nexin 9”. X-ray diffraction, 1 ligand (SO4), 7 pockets (best druggability 0.60). MolNFT v1 #50173 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2RAJ
- Type
- protein
- Length
- 382 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sorting nexin-9
- UniProt
- Q9Y5X1
- Ligands
- SO4
- Pockets
- 7 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 64% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-9 | protein | 382 | 64% helix, 9% strand | Q9Y5X1 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 299 | 0.60 | 0.78 | 38 | empty |
| 2 | 96 | 0.48 | 0.81 | 26 | empty |
| 3 | 146 | 0.45 | 0.75 | 16 | SO4 |
| 4 | 72 | 0.31 | 0.74 | 12 | empty |
| 5 | 53 | 0.30 | 0.76 | 9 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5X1
- Elsewhere: RCSB PDB 2RAJ · PDBe 2RAJ · UniProt Q9Y5X1
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