MolNFT v1 · #50097 · protein
Crystal structure of the long-chain fatty acid transporter fadl mutant delta S3 kink
2R88 · Long-chain fatty acid transport protein: “Crystal structure of the long-chain fatty acid transporter fadl mutant delta S3 kink”. X-ray diffraction, 6 pockets (best druggability 0.86). MolNFT v1 #50097 on GenesisL1: 3D structure…
- PDB
- 2R88
- Type
- protein
- Length
- 730 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Long-chain fatty acid transport protein
- UniProt
- P10384
- Pockets
- 6 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 10% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Long-chain fatty acid transport protein | protein | 365 | 10% helix, 55% strand | P10384 |
Pockets
6 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 806 | 0.86 | 0.89 | 93 | empty |
| 2 | 793 | 0.86 | 0.88 | 89 | empty |
| 3 | 296 | 0.70 | 0.83 | 36 | empty |
| 4 | 486 | 0.69 | 0.79 | 36 | empty |
| 5 | 379 | 0.61 | 0.77 | 34 | empty |
Interfaces
1 interface between chains.
- A–B · 687 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 2R88 · Crystal structure of the long-chain fatty acid transporter FadL mutant delta S3 kink · the same entry in another collection · chain A against A, TM-score 1.00
- P10384 · AlphaFold monomer V2.0 prediction for long-chain fatty acid transport protein (P10384) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10384
- Elsewhere: RCSB PDB 2R88 · PDBe 2R88 · UniProt P10384
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.