MolNFT v1 · #50027 · protein

Complex structure of sucrose phosphate synthase (sps)-F6P of halothermothrix orenii

2R66 · Glycosyl transferase, group 1: “Complex structure of sucrose phosphate synthase (sps)-F6P of halothermothrix orenii”. X-ray diffraction, 1 ligand (F6P), 4 pockets (best druggability 0.37). MolNFT v1 #50027 on GenesisL1: 3D…

PDB: 2R66
Type: protein
Length: 456 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyl transferase, group 1
EC: 2.4.1.14
UniProt: Q2ADF5
Ligands: F6P
Pockets: 4 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycosyl transferase, group 1 (EC 2.4.1.14)	protein	456	47% helix, 17% strand	Q2ADF5

Ligands and binding sites

F6P · 6-O-phosphono-beta-D-fructofuranose · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.37	0.79	22	F6P
2	67	0.34	0.76	17	empty
3	84	0.32	0.73	21	empty
4	63	0.31	0.76	19	empty

Compared structures

2R66 · Complex Structure of Sucrose Phosphate Synthase (SPS)-F6P of Halothermothrix orenii · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2ADF5
Elsewhere: RCSB PDB 2R66 · PDBe 2R66 · UniProt Q2ADF5

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